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The Science of Antioxidants

There are many glutathione products that claim to raise serum GSH levels by providing precursors. These will only raise GSH levels if the individual is already lacking in these precursors and/or still has the intracellular equipment working to create GSH. Once these precursors are replaced there would be no benefit to supplying more.

This does not solve the problem of reduced production and recycling of GSH as we age or as disease processes impede our ability to keep optimal levels.

One example of what declining GSH does to the body is demonstrated by the immune system. Immune surveillance. CD4+ T-cells need a good supply of GSH to properly function in recognizing and signalling other components of the immune system to target cells that have been infected by viruses, bacteria, have become cancerous or otherwise have been mutated or modified by toxins or free radicals.  

It is well established that our bodies use endogenous GSH to keep our melanocytes from transitioning to melanomas. A good analogy is that our immune system uses GSH as fuel. This is of course an oversimplification, but without going into nearly infinite biochemical detail, the analogy is valid.

Our livers use GSH to conjugate alcohol, acetaminophen and countless other electrophiles and/or toxins that could cause irreversible organ damage. Heavy metals such as arsenic, lead and mercury are removed from our bodies with the use of GSH.

GSH and other antioxidants protect us from macular degeneration and macular dystrophy. Accumulation of toxins and free-radicals cause damage that make us feel bad, make us look bad, and could be prevented.  GSH is vital for DNA repair and replication.

Low GSH levels have been associated with both hearing and visual impediments as we age.

Low GSH levels are observed in the pleural fluid of COPD patients, cystic fibrosis patients and some forms of asthma.

GSH is vital for proper kidney function, proper liver function, proper lung function and proper immune function, (including defense from cold and flu).  

There are over 86,000 published in the medical literature on the subject of glutathione (so don't take our word for it... do your own homework).